INVESTIGATION OF MOLECULAR MECHANISMS OF EXPERIMENTAL COMPOUNDS IN MURINE MODELS OF CHRONIC ALLERGIC AIRWAYS DISEASE USING SYNCHROTRON FOURIER-TRANSFORM INFRARED MICROSPECTROSCOPY

Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy

Abstract The ovalbumin-induced (OVA) chronic allergic airways murine model is a well-established model for investigating pre-clinical therapies for chronic allergic airways diseases, such as asthma.Here, we examined the effects of several experimental compounds with potential anti-asthmatic effects including resveratrol (RV), relaxin (RLN), l-sulfo

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